Journal of Clinical Lipidology
Volume 4, Issue 1 , Pages 46-52, January 2010

A secondary prevention lipid clinic reaches low-density lipoprotein cholesterol goals more often than usual cardiology care with coronary heart disease

  • Kim K. Birtcher, MS, PharmD

      Affiliations

    • University of Houston College of Pharmacy, Houston, TX
  • ,
  • Anthony J. Greisinger, PhD

      Affiliations

    • Kelsey Research Foundation, 5615 Kirby Drive, Suite 660, Houston, TX 77005
    • Corresponding Author InformationCorresponding author.
  • ,
  • Brenda J. Brehm, MA

      Affiliations

    • Kelsey Research Foundation, 5615 Kirby Drive, Suite 660, Houston, TX 77005
  • ,
  • Oscar A. Wehmanen, MS

      Affiliations

    • Kelsey Research Foundation, 5615 Kirby Drive, Suite 660, Houston, TX 77005
  • ,
  • Loriann M. Furman, PharmD

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX
  • ,
  • Cathryn C. Salinas, RPh

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX
  • ,
  • Madjid Mirzai-Tehrane, MD

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX
  • ,
  • Atasu Nayak, MD

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX
  • ,
  • Haroonur Rashid, MD

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX
  • ,
  • Ali Mortazavi, MD

      Affiliations

    • Kelsey-Seybold Clinic, Houston, TX

Received 14 September 2009; accepted 3 December 2009. published online 14 December 2009.

Objective

The objective of this study was to determine whether enrollment in a multidisciplinary secondary prevention lipid clinic (SPLC) for 3 or more years was associated with improved adherence to lipid guidelines as compared with usual care provided by cardiologists.

Methods

Patients with documented coronary artery disease (CAD), enrolled in a SPLC, and followed for at least 3 years were identified by the use of a computer database. The comparison group included patients with CAD who received usual care from a cardiologist during the same time period. The percentage of patients achieving low-density lipoprotein cholesterol (LDL-C) goals at enrollment and after at least 3 years of follow-up was determined for both groups. The average total cholesterol, LDL-C, high-density lipoprotein cholesterol (HDL-C), and triglycerides were determined after at least 3 years of follow-up for both groups.

Results

Patients enrolled in the SPLC reached the LDL-C goals more often than usual care cardiology patients (goal <100mg/dL: 81.9% vs. 72.8%, P < .001; optional goal <70mg/dL: 41.9% vs. 28.6%, P < .001). The patients enrolled in the SPLC had lower average total cholesterol, triglycerides, and LDL-C and greater average HDL-C after 3 years. All the lipid parameters decreased for patients in usual cardiology care, but these changes were not statistically significant.

Conclusions

This multidisciplinary secondary prevention lipid clinic achieved the LDL-C goals (<100mg/dL and optional goal <70mg/dL) more often than usual cardiology care for patients with CAD after 3 years of lipid management.

Keywords: Coronary artery disease, Guideline adherence, LDL-C goal, Lipid clinic, Multidisciplinary clinic, NCEP guidelines, Pharmacist, Prevention, Quality improvement

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PII: S1933-2874(09)00443-7

doi:10.1016/j.jacl.2009.12.001

Journal of Clinical Lipidology
Volume 4, Issue 1 , Pages 46-52, January 2010