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Volume 4, Issue 1, Pages 46-52 (January 2010)


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A secondary prevention lipid clinic reaches low-density lipoprotein cholesterol goals more often than usual cardiology care with coronary heart disease

Kim K. Birtcher, MS, PharmDa, Anthony J. Greisinger, PhDbCorresponding Author Informationemail address, Brenda J. Brehm, MAb, Oscar A. Wehmanen, MSb, Loriann M. Furman, PharmDc, Cathryn C. Salinas, RPhc, Madjid Mirzai-Tehrane, MDc, Atasu Nayak, MDc, Haroonur Rashid, MDc, Ali Mortazavi, MDc

Received 14 September 2009; accepted 3 December 2009. published online 14 December 2009.

Objective

The objective of this study was to determine whether enrollment in a multidisciplinary secondary prevention lipid clinic (SPLC) for 3 or more years was associated with improved adherence to lipid guidelines as compared with usual care provided by cardiologists.

Methods

Patients with documented coronary artery disease (CAD), enrolled in a SPLC, and followed for at least 3 years were identified by the use of a computer database. The comparison group included patients with CAD who received usual care from a cardiologist during the same time period. The percentage of patients achieving low-density lipoprotein cholesterol (LDL-C) goals at enrollment and after at least 3 years of follow-up was determined for both groups. The average total cholesterol, LDL-C, high-density lipoprotein cholesterol (HDL-C), and triglycerides were determined after at least 3 years of follow-up for both groups.

Results

Patients enrolled in the SPLC reached the LDL-C goals more often than usual care cardiology patients (goal <100mg/dL: 81.9% vs. 72.8%, P < .001; optional goal <70mg/dL: 41.9% vs. 28.6%, P < .001). The patients enrolled in the SPLC had lower average total cholesterol, triglycerides, and LDL-C and greater average HDL-C after 3 years. All the lipid parameters decreased for patients in usual cardiology care, but these changes were not statistically significant.

Conclusions

This multidisciplinary secondary prevention lipid clinic achieved the LDL-C goals (<100mg/dL and optional goal <70mg/dL) more often than usual cardiology care for patients with CAD after 3 years of lipid management.

a University of Houston College of Pharmacy, Houston, TX

b Kelsey Research Foundation, 5615 Kirby Drive, Suite 660, Houston, TX 77005

c Kelsey-Seybold Clinic, Houston, TX

Corresponding Author InformationCorresponding author.

PII: S1933-2874(09)00443-7

doi:10.1016/j.jacl.2009.12.001


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