Background
Statins substantially reduce the risk of cardiovascular disease and are generally
well-tolerated. Despite this, many patients discontinue therapy. A better understanding
of the characteristics of current and former statin users may be helpful for formulating
strategies to improve long-term adherence.
Objective
The Understanding Statin Use in America and Gaps in Education (USAGE) survey assessed
the attitudes, beliefs, practices, and behavior of current and former statin users.
Methods
Individuals 18 years or older who reported a history of high cholesterol and current
or former statin use were identified within a registered consumer panel cohort in
the United States and invited to participate in an Internet survey.
Results
Of the 10,138 respondents, 8918 (88%) were current statin users and 1220 (12%) were
former users. Participants (mean age 61 years) were predominantly white (92%), female
(61%), of middle income (median $44,504/yr), and had health insurance (93%). Among
current users, 95% took a statin alone, and 70% had not missed a dose in the past
month. Although ∼70% reported that their physicians had explained the importance of
cholesterol levels for their heart health former users were less satisfied with the
discussions (65% vs. 83%, P < .05). Muscle-related side effects were reported by 60% and 25% of former and current
users, respectively (P < .05). Nearly half of all respondents switched statins at least once. The primary
reason for switching by current users was cost (32%) and the primary reason for discontinuation
was side effects (62%).
Conclusions
This survey provides important insights into behavior and attitudes among current
and former statin users and the results suggest that more effective dialogue between
healthcare providers and patients may increase persistence of statin use, particularly
when the patient has concerns about side effects and drug costs.
Keywords
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Article info
Publication history
Accepted:
March 16,
2012
Received:
March 8,
2012
Identification
Copyright
© 2012 National Lipid Association. Published by Elsevier Inc. All rights reserved.
