- •CMEC quantifies net movement of cholesterol between cells and HDL.
- •We determined the association of CMEC with CAC.
- •Higher CMEC levels were not associated with lower CAC score or higher CAC density.
- •CV risk associated with HDL CMEC appears unrelated to calcified plaque burden.
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Conflict of interest: The authors declare that they have no conflicts of interest.
Authors’ contributions: Garg, Tressel, and McClelland had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Concept and design: Garg, Tall, Shea. Acquisition, analysis, or interpretation of data: All authors. Critical revision of the manuscript for important intellectual content: All authors. Statistical analysis: Tressel, McClelland. Supervision: Garg, Shea.