- •Non-statin lipid-lowering therapies reduce residual ASCVD risk.
- •Utilization of non-statin therapies is low for secondary prevention.
- •There has been limited uptake of non-statin therapies in the last several years.
- •Increasing use of these therapies is paramount to improving the treatment gap.
Abbreviations:ASCVD (atherosclerotic cardiovascular disease), PCSK9i (proprotein convertase subtilisin/kexin type 9 inhibitors), EHR (electronic health record), LLT (lipid-lowering therapies)
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Disclosure: AM Navar has received funding for research to her institution from BMS, Esperion, and Janssen, and honoraria and consulting fees from Astra Zeneca, BI, Bayer, Janssen, Lilly, Novo Nordisk, Novartis, New Amsterdam, Cerner, and Pfizer. NP Shah has received research funding from Amgen, Janssen, and Novartis, and honoraria and consulting fees from Amgen, Novartis, and Esperion. ED Peterson has received research funding to his institution from BMS, Esperion, Janssen, and Amgen, and honoraria and consulting fees from Bayer, Novo Nordisk, Cerner Enviza, and Novartis. CK Bradley, AA Kolkailah, and C Page have nothing to disclose.
Authors contributions: AMN and CBP had full access to the data in the study and take responsibility for the accuracy of the data analysis. CKB, AAK, NPS, EDP, and AMN were responsible for study concept and design. AMN and CBP were responsible for data analysis. CKB was responsible for drafting the article. CKB, AAK, NPS, EDP, and AMN were responsible for critically revising the article. All listed authors have approved the final manuscript.
Funding: This project was supported by grant funding to Duke University and UT Southwestern Medical Center from Janssen. The sponsor had no role in the development of the analytic plan, data analysis, data interpretation, or decision to publish.